Semaglutide Microdose Melts are a dissolvable, oral form of semaglutide designed to provide a gentler, more approachable path to metabolic wellness. Instead of an injection, the melt is placed between your cheek and gums (or under the tongue), where it dissolves slowly and is absorbed through the mucous membranes. This method allows the semaglutide to efficiently enter the body, while offering a needle-free, well-tolerated experience.

SEMAGLUTIDE MICRODROSE MELTS AT-A-GLANCE:
WHAT IS IT:
An oral form of semaglutide for daily use.
BENEFITS:
Designed to improve energy, focus, sleep, and longevity.
PROGRAM LENGTH:
Ongoing monthly prescription provided by Von & Co Aesthetics
SUPPORT:
Regular check-ins and provider access 7 days a week.
Why Semaglutide Microdose Melts?
Semaglutide Microdose Melts are a dissolvable, oral form of semaglutide created for those seeking a gentle, approachable path to metabolic wellness. Semaglutide mimics natural gut hormones to slow digestion, thereby improving the body’s ability to regulate blood sugar for stable energy, reduced cravings, and long-term metabolic health. Better glucose control also helps lower inflammation in the body, supporting whole-body wellness.
We designed this unique semaglutide in Naples program to make optimizing metabolic health accessible, sustainable, and effective. With consistent use, guests have experienced the following:
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Boosts steady energy and reduces fatigue
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Elevates focus and mental clarity
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Reduces cravings
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Improves sleep quality
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Supports heart health and hormonal balance

What to Expect

Consultation
During your personalized wellness consultation, our providers will discuss your wellness goals and design a tailored treatment plan to support your journey.

Routine
Take one melt daily, at the same time each day. Place it between your cheek and gums and allow it to dissolve slowly for best absorption.

Support
Most guests begin to notice benefits in 4-6 weeks. We’ll check in with you regularly—our team is always available to support you 7 days a week.
Physician-Led Aesthetic Care
Our highly trained team of providers are experts in their fields and have over 35 years of combined experience in aesthetics.
Tailored Experiences
Everyone is treated as an individual. Our bespoke treatment plans and exceptional service help you feel restored, inside and out.
Ultimate Convenience
Scheduling your self-care should be easy. That’s why we’re open 7 days a week, including evening hours on Wednesday and Thursday.
Award-winning AESTHETIC CARE
2025 Winner!
Best of The Gulfshore &
Naples Community’s Choice
Best Med Spa | Best Injectables | Best Facials
We are thrilled to have won both The Best of The Gulfshore and Naples Community’s Choice awards. We are inspired by our guests and are passionate about delivering best-in-class outcomes through exceptional, curated experiences to all we serve.
Thank you to all who voted for us—we are honored to care for this wonderful community.

Discover the possibilities
Which services are right for you?
Our Personalized Treatment Finder provides recommendations based on your specific concerns. When you’re ready to get started, book a complimentary consultation with one of our experts who will discuss these options and develop a personalized plan to reach your goals.

Frequently Asked Questions
Semaglutide is a GLP-1 (glucagon-like peptide-1) receptor agonist that mimics natural gut hormones to help sustain your energy and metabolism throughout the day. Because metabolic health influences so many aspects of well-being—from mood and focus to sleep, skin, and long-term vitality — supporting balance at this level may have wide-reaching benefits. Microdosing semaglutide is designed to promote whole-body wellness in a gentle, sustainable way.
With consistent use, semaglutide microdosing may help maintain steady energy and reduce fatigue. Many people also experience improved focus, mental clarity, and concentration as well as reduced cravings throughout the day. Semaglutide has additionally been shown to reduce inflammation, which supports cardiovascular and skin health, helps slow the aging process, and may contribute to increased longevity.
Microdosing offers an oral, lower-dose alternative to injectable semaglutide in Naples treatments. Our melts are designed to be very tolerable, with a slower build-up in your system. This makes it a good option for those who want a gentle, sustainable approach to wellness rather than rapid weight change.
No—our Semaglutide Microdose Melt program is designed to support whole-body wellness. By gently influencing cravings, energy, and metabolism, microdosing may help promote balance in many areas of health, from steady energy to improved focus and vitality.
Because the semaglutide dose is smaller than standard weight-loss prescriptions, benefits develop gradually. Many guests notice improvements in energy, focus, sleep, appetite and energy levels within 4–6 weeks, with continued progress over time.
Weeks 1–2: You may notice a reduction in cravings. Mild nausea or bloating can occur but usually improve as your body adjusts. Many people also describe more even energy levels as their blood sugar begins to stabilize.
Weeks 3–6: Early benefits often include clearer focus and a more consistent sense of balance, from energy levels to appetite, throughout the day. These shifts reflect semaglutide’s support in regulating blood sugar and improving how the body processes food, which in turn helps reduce energy spikes and crashes.
Weeks 4–8: Wellness benefits often become more noticeable, including improved digestion, reduced inflammation, and support for healthy cholesterol and blood pressure. Many also report steadier energy throughout the day, more consistent digestion, and measurable improvements in blood sugar and cholesterol, all of which contribute to stronger metabolic and cardiovascular health.
Ongoing: With consistency and a healthy lifestyle, semaglutide continues to provide meaningful health benefits which may include: long-term blood sugar regulation, reduced inflammation, sustained cardiovascular support, healthier skin, and more stable energy. Over time, these effects contribute to healthier aging, improved vitality, and better overall quality of life.
Semaglutide has been extensively researched and proven effective. Oral microdosing is a newer, gentler approach designed to improve tolerability and make semaglutide more accessible—especially for those who want the benefits without injections or who aren’t seeking dramatic weight loss, but want the other benefits of optimal metabolic health. While it may not be the right fit for everyone, safety is always our priority. That’s why every program is guided by our physician-led team, with personalized care and ongoing support at every step.
The most common side effects are mild nausea, bloating, increased bowel movements, and headache, especially in the first weeks as your body adjusts. These typically improve with time. Severe side effects are rare and unexpected, but we provide guidance on when to contact us immediately.
This program is ideal for adults who want to support energy, focus, sleep, clarity, appetite and overall vitality and longevity. It is not recommended during pregnancy, breastfeeding, or for those with certain medical conditions. Your consultation will determine if it’s right for you.
Our providers will review your full medical history to ensure safety and avoid interactions, especially with diabetes or weight-related medications.
Call us at 239.799.4VON(4866) to schedule your complimentary wellness consultation. Our team will guide you through the entire process and tailor our semaglutide in Naples program to your needs. We look forward to meeting you.
Focused on You.
At Von & Co Medical Aesthetics Studio, our focus is on giving you the best experience possible. The highly skilled, passionate members of our team are experts at helping you achieve your unique skin care and wellness goals, at hours that are convenient for you. We look forward to welcoming you into our studio.
